Aplicação de LC-SPE/NMR na rápida identificação de compostos orgânicos em fitoterápico

Autores/as

  • Sérgio Scherrer Thomasi
  • Lyege Magalhães Oliveira
  • Tiago Venâncio
  • Antonio Gilberto Ferreira

DOI:

https://doi.org/10.18554/rbcti.v2i1.776

Palabras clave:

LC-SPE/NMR, Ilex paraguariensis, hifenação

Resumen

Este artigo descreve a análise do perfil químico de um medicamento fitoterápico à base de Ilex paraguariensis utilizando a tecnologia acoplada LC-SPE/NMR, que levou à rápida separação e identificação de oito compostos orgânicos em um único experimento. Dessa forma, metodologias clássicas de isolamento não foram necessárias. A alta seletividade alcançada na separação cromatográfica, somada à adequada retenção por SPE e a aplicação da tecnologia criogênica de RMN de alto campo magnético (14,1 Tesla) permitiu a obtenção de dados conclusivos acerca das estruturas encontradas, eliminando a necessidade de experimentos por espectrometria de massa.

Biografía del autor/a

Sérgio Scherrer Thomasi

Departamento de Química. Área: Química Orgânica.

Citas

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Publicado

2018-02-28

Cómo citar

Thomasi, S. S., Oliveira, L. M., Venâncio, T., & Ferreira, A. G. (2018). Aplicação de LC-SPE/NMR na rápida identificação de compostos orgânicos em fitoterápico. REVISTA BRASILEÑA DE CIENCIA, TECNOLOGÍA E INNOVACIÓN, 2(1), 13–22. https://doi.org/10.18554/rbcti.v2i1.776