Early diagnosis of hepatitis C by primary health care
DOI:
https://doi.org/10.18554/refacs.v9i0.4242Keywords:
Primary health care, Hepatitis C, Prevalence, Epidemiology, Early diagnosis.Abstract
This is an exploratory, descriptive, cross-sectional, retrospective study with an epidemiological approach, carried out in primary health care units in the city of Uberaba between 2014 and March of 2017. It aimed to know the prevalence and positivity of the Anti-hepatitis C antibody in adult population over 40 years. 17,845 people were tested using the immunochromatographic test and then the 131 positives were tested for genotyping and liver fibrosis staging. It was found 0.73% of positives, 79.3% of whom were born in the 1950s to 1970s; and 24% had moderate liver fibrosis, advanced liver fibrosis or cirrhosis. The most cited forms of transmission were drug use (any route); multiple sexual partners and transfusions, hemodialysis or organ transplantation. It is important to train professionals in the primary care network on the importance of hepatitis C, its early diagnosis and priority risk groups, in addition to providing greater access to diagnosis.
References
Mbituyumuremyi A, Van Nuil JI, Umuhire J, Mugabo J, Mwumvaneza M, Makuza JD, et al. Controlling hepatitis C in Rwanda: a framework for a national response. Bull World Health Organ. [Internet]. 2018 [citado em 19 jan 2021]; 96(1):51-8. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791867/. DOI: 10.2471/BLT.16.183772
Hepatitis C: global ambition, national realities (editorial). Lancet [Internet]. 2016 [citado em 19 jan 2021]; 387(10032):1970.
Baptista-González H, Nofal-Nuño VM, Méndez-Sánchez N. Frequency of hepatitis C virus infection in a single institution in Mexico with a focus on birth-cohort population. Ann Hepatol. [Internet]. 2016 [citado em 19 jan 2021]; 15(6):846-52. DOI: 10.5604/16652681.1222100
Thrift AP, El-Serag HB, Kanwal F. Global epidemiology and burden of HCV infection and HCV-related disease. Nat Rev Gastroenterol Hepatol. [Internet]. 2017 [citado em 19 jan 2021]; 14(2):122-32. DOI: 10.1038/nrgastro.2016.176
Adland E, Jesuthasan G, Downs, L, Wharton V, Wilde G, McNaughton AL, et al. Hepatitis virus (HCV) diagnosis and access to treatment in a UK cohort. BMC Infect Dis. [Internet]. 2018 [citado em 19 jan 2021]; 18(1):461. DOI: 10.1186/s12879-018-3367-3
World Health Organization. Global health sector strategy on viral hepatitis 2016–2021 [Internet]. Geneva: WHO; 2016 [citado em 9 jan 2020]. Disponível em: https://www.who.int/hepatitis/strategy2016-2021/ghss-hep/en/
Akiyama MJ, Kaba F, Rosner Z, Alper H, Holzman RS, MacDonald R. Hepatitis C screening of the "Birth Cohort" (Born 1945-1965) and younger inmates of New York City Jails. Am J Public Health [Internet]. 2016 [citado em 19 jan 2021]; 106(7):1276-7. DOI: 10.2105/AJPH.2016.303163
Smith BD, Morgan RL, Beckett GA, Falck-Ytter Y, Holtzman D, Teo CG, et al. Recommendations for the identification of chronic hepatitis C virus infection among persons born during 1945-1965. MMWR Recomm Rep. [Internet]. 2012 [citado em 19 jan 2021]; 61(RR-4):1-32. Disponível em: https://pubmed.ncbi.nlm.nih.gov/22895429/
Ministério da Saúde (Brasil), Secretaria de Vigilância em Saúde,Departamento de Vigilância, Prevenção e controle das IST, do HIV/Aids e das hepatites virais [Internet]. Brasília, DF: Ministério da Saúde; 2019 [citado em 9 jan 2020]. (Plano para eliminação da hepatite C no Brasil). Disponível em: http://www.aids.gov.br/pt-br/pub/2019/plano-para-eliminacao-da-hepatite-c-no-brasil
Oliveira AC, Bortotti AC, Nunes NN, El Bacha IA, Parise ER. Association between age at diagnosis and degree of liver injury in hepatitis C. Braz J Infect Dis. [Internet]. 2014 [citado em 19 jan 2021]; 18(5):507-11. DOI: https://doi.org/10.1016/j.bjid.2014.04.003
Focaccia R, Conceição OJ, Sette Junior H, Sabino E, Bassit L, Nitrini DR, et al. Estimated prevalence of viral hepatitis in the general population of the Municipality of São Paulo, measured by a serologic survey of a stratified, randomized and residence-based population. Braz J Infect Dis. 1998; 2(6):269-84.
Pereira LMMB, Martelli CMT, Moreira RC, Merchan-Hamman E, Stein AT, Cardoso MRA, et al. Prevalence and risk factors of Hepatitis C virus infection in Brazil, 2005 through 2009: a cross-sectional study. BMC Infect Dis. [Internet]. 2013 [citado em 19 jan 2021]; 13:60. DOI: 10.1186/1471-2334-13-60
Secretaria de Estado da Saúde de Minas Gerais. Estudo de prevalência de base populacional das hepatites virais B e C nas 13 macrorregiões do estado de Minas Gerais. Uma abordagem das doenças e agravos transmissíveis no panorama estadual. Inf Epidemiol. 2014:12-23.
Gomide GP, Melo CB, Santos VS, Salge VD, Camargo FC, Pereira GA. Epidemiological survey of hepatitis C in a region considered to have high prevalence: the state of Minas Gerais, Brazil. Rev Soc Bras Med Trop. [Internet]. 2019 Oct 3 [citado em 19 jan 2021]; 52:e20190202. DOI: 10.1590/0037-8682-0202-2019
Instituto Brasileiro de Geografia e Estatística. Minas Gerais. Uberaba [Internet]. Rio de Janeiro: IBGE; 2019 [citado em 9 jan 2020]. Disponível em: https://cidades.ibge.gov.br
Ministério da Saúde (Brasil), Secretaria de Vigilância em Saúde, Departamento de Vigilância, Prevenção e controle das IST, do HIV/Aids e das hepatites virais [Internet]. Brasília, DF: Ministério da Saúde; 2019 [citado em 9 jan 2020]. (Protocolo clínico e diretrizes terapêuticas para hepatite C e coinfecções). Disponível em: http://www.aids.gov.br/pt-br/pub/2017/protocolo-clinico-e-diretrizes-terapeuticas-para-hepatite-c-e-coinfeccoes
Richard JL, Schaetti C, Basler S, Mäusezahl M. The epidemiology of hepatitis C in Switzerland: trends in notifications, 1988-2015. Swiss Med Wkly. [Internet]. 2018 [citado em 19 jan 2021]; 148:w14619. DOI: 10.4414/smw.2018.14619
American Association for the Study of Liver Diseases, Infectious Diseases Society of America. Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus. Hepatology [Internet]. 2015 [citado em 19 jan 2021]; 62(3):932-54. DOI: 10.1002/hep.27950
Gómez-Escolar Viejo L, García Herola A, Sáez Lloret I, Sánchez Ruano F, Clemente Paulino I, Quílez Ivorra C, et al. Screening of hepatitis C virus infection in adult general population in Spain. Eur J Gastroenterol Hepatol. [Internet]. 2018 [citado em 19 jan 2021]; 30(9):1077-81. DOI: 10.1097/MEG.0000000000001190
Bruggmann P, Berg T, Øvrehus AL, Moreno C, Brandão Mello CE, Roudot-Thoraval F, et al. Historical epidemiology of hepatitis C vírus (HCV) in selected countries. J Viral Hepat. [Internet]. 2014 [citado em 19 jan 2021]; 21(Suppl 1):5-33. DOI: 10.1111/jvh.12247
Ministério da Saúde (Brasil), Secretaria de Vigilância em Saúde, Departamento de Doenças de Condições Crônicas e Infecções Sexualmente Transmissíveis. Hepatites virais 2019. Bol Epidemiol. [Internet]. 2019 [citado em 9 jan 2020]; 17(50):1-71. Disponível em: http://www.aids.gov.br/pt-br/pub/2019/boletim-epidemiologico-de-hepatites-virais-2019
Presidência da República (Brasil), Casa Civil, Subchefia para Assuntos Jurídicos. Lei nº 9.273, de 3 de maio de 1996. Torna obrigatória a inclusão de dispositivo de segurança que impeça a reutilização das seringas descartáveis. Diário Oficial União [Internet]. 1996 [citado em 19 jan 2021]; 1:7625. Disponível em: https://www2.camara.leg.br/legin/fed/lei/1996/lei-9273-3-maio-1996-372353-publicacaooriginal-1-pl.html
Harm Reduction International. The global state of harm reduction 2018 [Internet]. 6thed. London: Phoenix Media Group; 2018 [citado em 17 jan 2020]. Disponível em: https://www.hri.global/global-state-harm-reduction-2018
Dore GJ, Ward J, Thursz M. Hepatitis C disease burden and strategies to manage the burden (Guest Editors Mark Thursz, Gregory Dore and John Ward). J Viral Hepat. [Internet]. 2014 [citado em 19 jan 2021]; 21(Suppl 1):1-4. DOI: 10.1111/jvh.12253
Aghemo A, Dore GJ, Hatzakis A, Wedemeyer H, Razavi H. Estimating HCV disease burden - volume 3 (editorial). J Viral Hepat. [Internet]. 2015 [citado em 19 jan 2021];22(Suppl 4):1-3. DOI: 10.1111/jvh.12473
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