IMPACTS OF AGING ON THE MALE REPRODUCTIVE SYSTEM: HORMONAL, METABOLIC AND REPRODUCTIVE CHANGES

Autores

  • Ana Clara Melo de Andrade Rodrigues Universidade Federal do Triângulo Mineiro https://orcid.org/0009-0005-6015-2537
  • Fernanda Carolina Ribeiro Dias Universidade Federal do Triângulo Mineiro
  • Marcos de Lucca Moreira Gomes

DOI:

https://doi.org/10.18554/t0m6f474

Palavras-chave:

reproduction, testicles, epididymis, elderly, aging

Resumo

Aging gradually affects the male genital system due to profound hormonal and metabolic changes. The reduction in the proportion of testicular blood vessels reduces the supply of oxygen and other nutrients to the organ's parenchyma, increasing inflammatory conditions and oxidative stress, which can significantly affect sperm viability and morphology. Aging has an impact on lipid and protein metabolism, which can compromise sperm structure and functionality. In addition, sperm can accumulate significant changes in their DNA, increasing the chance of mutations with consequent harmful consequences for their offspring, such as autism spectrum disorders, schizophrenia, and attention deficit disorders. Therefore, understanding the male aging process and its consequences for men's reproductive health is of utmost importance for the prevention and treatment of diseases related to the male genital tract.

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Publicado

05-06-2025

Edição

v. 8 n. 1 (2025)

Seção

Revisão da Literatura

Como Citar

IMPACTS OF AGING ON THE MALE REPRODUCTIVE SYSTEM: HORMONAL, METABOLIC AND REPRODUCTIVE CHANGES. Acta Biologica Brasiliensia, [S. l.], v. 8, n. 1, p. 290–300, 2025. DOI: 10.18554/t0m6f474. Disponível em: https://seer.uftm.edu.br/revistaeletronica/index.php/acbioabras/article/view/8273. Acesso em: 7 nov. 2025.