IN VITRO EFFECTS OF POLYSTYRENE NANOPLASTICS ON HUMAN SPERM MOTILITY AND MITOCHONDRIAL ACTIVITY

Autores

  • Beatriz Teixeira de Oliveira Universidade Federal do Triângulo Mineiro
  • Camila Santos de Carvalho Universidade Federal do Triângulo Mineiro
  • Cristiana Livramento Oliveira Pinto Universidade Federal do Triângulo Mineiro
  • Nicoly Caixêta Gonçalves Universidade Federal do Triângulo Mineiro
  • Hugo Felix Perini Universidade Federal do Triângulo Mineiro
  • Gláucia Siervo Universidade Federal do Triângulo Mineiro

DOI:

https://doi.org/10.18554/acbiobras.v8i2.8765

Palavras-chave:

Plástico, Gameta, Mitocôndria, Reprodução

Resumo

It is estimated that approximately 350 million tons of plastic become waste through physical and chemical processes, generating microplastics and nanoplastics. Considering the increasing global production of plastics and their potential environmental and human health impacts, this study evaluated the effects of polystyrene nanoplastics (PS-NP) on human sperm parameters in vitro. Spermatozoa from healthy volunteers (n=7) were collected and included only if the samples met the World Health Organization’s normality criteria. Cells were isolated using the swim-up technique in BWW medium and exposed to PS-NP at concentrations of 2, 20, and 200 μg/mL, along with a control group, for 30 and 120 minutes. Sperm motility and mitochondrial activity were assessed. The results showed that intermediate and high concentrations significantly reduced motility and mitochondrial functionality in a concentration- and time-dependent manner. These findings suggest that PS-NPs may impair critical functions for male fertility, highlighting the need for further studies to clarify the underlying mechanisms and reproductive health risks.

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Publicado

31-10-2025

Edição

v. 8 n. 2 (2025)

Seção

Artigos

Como Citar

OLIVEIRA, Beatriz Teixeira de; CARVALHO, Camila Santos de; PINTO, Cristiana Livramento Oliveira; GONÇALVES, Nicoly Caixêta; PERINI, Hugo Felix; SIERVO, Gláucia. IN VITRO EFFECTS OF POLYSTYRENE NANOPLASTICS ON HUMAN SPERM MOTILITY AND MITOCHONDRIAL ACTIVITY. Acta Biologica Brasiliensia, [S. l.], v. 8, n. 2, p. 437–449, 2025. DOI: 10.18554/acbiobras.v8i2.8765. Disponível em: https://seer.uftm.edu.br/revistaeletronica/index.php/acbioabras/article/view/8765. Acesso em: 18 dez. 2025.