Cardiac weight in elderly men with chronic chagas heart disease

Flávia Aparecida Oliveira; Joana Estela Rezende Vilela; Larissa Oliveira Queiroz; Douglas Montielle Silva Nascimento; Vicente de Paula Antunes Teixeira; Eliza Carla Barroso Duarte; Liliana Borges Menezes; Juliana Reis Machado; Marlene Antônia Reis

doi:10.18554/refacs.v5i3.1994

Autores/as

Flávia Aparecida Oliveira Department of Pathology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia - Goiás, Brazil http://orcid.org/0000-0001-7881-6024
Joana Estela Rezende Vilela Department of Pathology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia - Goiás, Brazil http://orcid.org/0000-0003-3449-0354
Larissa Oliveira Queiroz Department of Pathology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia - Goiás, Brazil http://orcid.org/0000-0002-9015-3507
Douglas Montielle Silva Nascimento Department of Pathology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia - Goiás, Brazil http://orcid.org/0000-0001-5918-0374
Vicente de Paula Antunes Teixeira Discipline of General Pathology, Federal University of Triângulo Mineiro, Uberaba, Minas Gerais, Brazil http://orcid.org/0000-0002-0195-8646
Eliza Carla Barroso Duarte Department of Pathology, School of Medicine, University of Brasília, Brasília, Brazil http://orcid.org/0000-0002-9492-5391
Liliana Borges Menezes Department of Pathology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia - Goiás, Brazil http://orcid.org/0000-0003-4237-6279
Juliana Reis Machado Department of Pathology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia - Goiás, Brazil http://orcid.org/0000-0002-8673-7788
Marlene Antônia Reis Discipline of General Pathology, Federal University of Triângulo Mineiro, Uberaba, Minas Gerais, Brazil http://orcid.org/0000-0002-8594-7636

DOI:

https://doi.org/10.18554/refacs.v5i3.1994

Palabras clave:

Envejecimiento, Cardiomiopatía Chagásica, Fibrosis

Resumen

El objetivo de este estudio fue correlacionar las alteraciones histopatológicas de la cardiopatía chagásica crónica con el peso cardíaco (Pca) en hombres ancianos. Fueron seleccionados 16 corazones con alteraciones morfológicas y sorología positiva (ancianos cc). Se cuantificaron en el miocardio izquierdo las espesuras de los miocardiocitos y sus núcleos, densidad del infiltrado mononuclear y de los núcleos de miocardiocitos y la fibrosis miocárdica. El Pca en los hombres ancianos CC fue 418,7 ±136,3g y presentó correlación positiva y significativa con la espesura de los miocardiocitos y de sus núcleos (rS=0,363 y rS=0,120, respectivamente p<0,05) y con la fibrosis intersticial (rS=0,104 p<0,05). Por otro lado, se verificó correlación negativa y no significativa entre el Pca y el infiltrado inflamatorio (rS=-0,0118 p>0.05). La densidad de núcleos de miocardiocitos presentó correlación negativa y significativa con el Pca (rS= -0,555 p<0,05). El aumento del Pca en los hombres ancianos cc fue influido por la fibrosis intersticial, así como por la hipertrofia miocárdica y destrucción de miocardiocitos.

Citas

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Peso cardíaco en hombres ancianos con cardiopatía chagásica crónica

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